nlmixr2est: The core estimation routines for nlmixr2

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The goal of nlmixr2est is to provide the nlmixr2 core estimation routines.

Installation

You can install the development version of nlmixr2est from GitHub with:

# install.packages("remotes")
remotes::install_github("nlmixr2/rxode2")
remotes::install_github("nlmixr2/nlmixr2data")
remotes::install_github("nlmixr2/lotri")
remotes::install_github("nlmixr2/nlmixr2est")

For most people, using nlmixr2 directly would be likely easier.

library(nlmixr2est)
#> Loading required package: nlmixr2data

## The basic model consists of an ini block that has initial estimates
one.compartment <- function() {
  ini({
    tka <- 0.45; label("Ka")
    tcl <- 1;…