VariantGrid

VariantGrid is a database and web application for storing, analysing and classifying variants.

Use cases

Public servers:

• VariantGrid.com - research focused instance, free user access

Collaborative data sharing sites:

• Shariant Australia - Australian Genomics variant interpretation sharing server
• RUNX1Db - Rare blood disease data sharing

Private servers:

• Clinical/diagnostic use by SA Pathology, the South Australian public pathology service.
• Research exomes by labs at the Centre for Cancer Biology

Analysis / curation

Upload VCFs to:

• Automatically annotate with Ensembl VEP
• See samples from all VCFs that share a variant
• Analyse and filter samples, trios or cohorts via real time drag & drop interactive analyses
• Classify variants using a customisable ACMG form
• GRCh37 (hg19), GRCh38, Ensembl and RefSeq in the same database (some automatic conversion)
• Manage and curate data, including patient phenotypes

Licensing

VariantGrid code is free to use for research and…